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February 2008 - Posts
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An update of the evidence on this topic, produced by the NLH Skin Disorders Specialist Library
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An update of the evidence on this topic, produced by the NLH Women's Health Specialist Library
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Results from a new national survey demonstrate that elevated allergen levels in the home are associated with asthma symptoms in allergic individuals. The study suggests that asthmatics that have allergies may alleviate symptoms by reducing allergen exposures inside their homes. The work was carried out by researchers at the National Institute of Environmental Health Sciences (NIEHS), the University of Iowa, Rho Inc., and the Constella Group. The team's findings may help millions of Americans who suffer from asthma.
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A small striped fish is helping scientists understand what makes people susceptible to a common form of hearing loss, although, in this case, it's not the fish's ears that are of interest. In a study published in the Feb. 29 issue of the journal "PLoS Genetics", researchers at the University of Washington have developed a research method that relies on a zebrafish's lateral line -- the faint line running down each side of a fish that enables it to sense its surroundings -- to quickly screen for genes and chemical compounds that protect against hearing loss from some medications. The study was funded in part by the National Institute on Deafness and Other Communication Disorders (NIDCD), one of the National Institutes of Health.
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The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) today announced the release of new health information to raise awareness about diabetes, digestive diseases, and kidney and urologic diseases among people not yet diagnosed with these illnesses. The NIDDK developed the Awareness and Prevention Series for community health fairs, workplace health forums, family reunions, and other similar events. NIDDK is one of the National Institutes of Health (NIH).
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Two targeted medications designed to treat an aggressive form
of breast cancer are being tested in a new study involving 8,000
participants in 50 countries across six continents -- a clinical
trial that investigators hope will provide a new model for global
cancer research. This trial, dubbed ALTTO (Adjuvant Lapatinib and-or
Trastuzumab Treatment Optimization study), will be one of the first
global initiatives in which two large, academic breast cancer research
networks covering different parts of the world have jointly developed
a study in which all care and data collection are standardized,
regardless of where patients are treated. The networks are The
Breast Cancer Intergroup of North America (TBCI), based in the
United States, and the Breast International Group (BIG) in Brussels,
Belgium. TBCI consists of six National Cancer Institute (NCI)-funded
clinical trials cooperative groups. NCI is part of the National
Institutes of Health.
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Women with bladder control problems can learn about treatments
and techniques to help them manage their condition in a new resource
from the National Kidney and Urologic Diseases Information Clearinghouse
(NKUDIC), an information dissemination service of the National
Institute of Diabetes and Digestive and Kidney Diseases (NIDDK),
one of the National Institutes of Health (NIH).
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An independent panel convened this week by the NIH concluded
that the use of hydroxyurea for sickle cell patients should
be increased in adolescents and adults. Hydroxyurea
was approved by the U.S. Food and Drug Administration for
use in adults with sickle cell anemia in 1998, but provider
and patient concerns have hindered its use, depriving many
patients of its proven benefits.
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Many older adults have their blood cholesterol level checked regularly. Now, easy-to-understand information about why this test is so important to heart health and what the results mean is available on NIHSeniorHealth, the National Institutes of Health (NIH) Web site designed especially for seniors.
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Millions of Britons are taking anti-depressants for no reason reported eight newspapers (26 February 2008). These reported conclusions of a meta-analysis, which showed a small benefit of certain antidepressants over placebo. Though reports were generally accurate, the analysis did not include all available data on the effects of these drugs.
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Teens with difficult-to-treat depression who do not respond to a first antidepressant medication are more
likely to get well if they switch to another antidepressant medication
and add psychotherapy rather than just switching to another antidepressant,
according to a large, multi-site trial funded by the National Institutes
of Health's National Institute of Mental Health (NIMH). The
results of the Treatment of SSRI-resistant Depression in Adolescents
(TORDIA) trial were published February 27, 2008, in the "Journal
of the American Medical Association" (JAMA).
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A brain circuit that underlies feelings of stress and anxiety shows promise as a new therapeutic target for alcoholism, according to new studies by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH).
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Idalia Ramos Sanchez, a longtime fighter for health equity
especially as it relates to HIV/AIDS, has been appointed senior
policy advisor at the National Center on Minority Health and
Health Disparities (NCMHD), National Institutes of Health (NIH).
She will serve as the primary legislative liaison within the
Division of Scientific Strategic Planning and Policy Analysis
(DSSPPA). DSSPPA is the coordination arm for the development
of NCMHD's strategic plan and responsible for assessing and
highlighting NIH's overall effort to eliminate health disparities.
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Rates of cognitive impairment among older Americans are on the
decline, according to a new study supported by the National Institutes
of Health (NIH) comparing the cognitive health of older people
in 1993 and 2002. Higher levels of education were associated with
better cognitive health.
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NHS Medical Search and Microsoft are due to release a number of tools to make searching easier in March.
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NHS Medical Search and Microsoft are due to release a number of tools to make searching easier in March.
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The National Eye Institute (NEI) of the National Institutes of
Health (NIH) announces the start of a multicenter clinical trial
to compare the relative safety and effectiveness of two drugs currently
used to treat advanced age-related macular degeneration (AMD).
The two drugs are Lucentis (ranibizumab) and Avastin (bevacizumab).
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In vitro fertilisation (IVF) using single embryo transfer boosts success and safety, reported five newspaper articles on 21 February 2008 (1-5). The generally accurate reports were based on a large before- and after-study that found beneficial effects of a single embryo transfer strategy aimed at a selected group of women.
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In vitro fertilisation (IVF) using single embryo transfer boosts success and safety, reported five newspaper articles on 21 February 2008 (1-5). The generally accurate reports were based on a large before- and after-study that found beneficial effects of a single embryo transfer strategy aimed at a selected group of women.
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A better understanding of how memory works is emerging from a
newfound ability to link a learning experience in a mouse to consequent
changes in the inner workings of its neurons. Researchers, supported
in part by the National Institutes of Health's National Institute
of Mental Health (NIMH), have developed a way to pinpoint the specific
cellular components that sustain a specific memory in genetically-engineered
mice.
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Smoking plays a role in lung cancer development, and now scientists
have shown that smoking also affects the way genes are expressed,
leading to alterations in cell division and regulation of immune
response. Notably, some of the changes in gene expression persisted
in people who had quit smoking many years earlier. These findings
by researchers at the National Cancer Institute (NCI), part of
the National Institutes of Health, appeared in the Feb. 20, 2008,
issue of "PLoS ONE".
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Experts will describe the available evidence
on hydroxyurea treatment for sickle cell disease, including
efficacy, effectiveness, harms, barriers to treatment,
and future research needs. Following a series of scientific
presentations and open public discussions, an impartial,
independent panel will issue a statement of its findings
on the final day of the conference, and will hold a press
conference at 2:00 p.m. on Wednesday, February 27. Convened
by the Office of Medical Applications of Research (OMAR)
and the National Heart, Lung, and Blood Institute (NHLBI)
of the NIH, this conference is free and open to the public
and the media.
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Diabetes is known to impair the cognitive health of people, but
now scientists have identified one potential mechanism underlying
these learning and memory problems. A new National Institutes
of Health (NIH) study in diabetic rodents finds that increased
levels of a stress hormone produced by the adrenal gland disrupt
the healthy functioning of the hippocampus, the region of the brain
responsible for learning and short-term memory.
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In laboratory experiments, scientists at the National Cancer Institute
(NCI), part of the National Institutes of Health (NIH), and their
colleagues supported by the NIH National Institute of Allergy and
Infectious Disease (NIAID), have discovered an antibody that neutralizes
two viruses classified as henipaviruses.
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An international team of researchers supported by the National
Institutes of Health (NIH) has blocked staph infections in mice
using a drug previously tested in clinical trials as a cholesterol-lowering
agent.
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Testing the safety of chemicals ranging from pesticides to household
cleaners will benefit from new technologies and a plan for collaboration,
according to federal scientists from the National Institutes of
Health (NIH) and the U.S. Environmental Protection Agency (EPA),
who today announced a new toxicity testing agreement.
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Current research supported by the National
Institute on Deafness and Other Communication Disorders (NIDCD),
one of the National Institutes of Health, will be featured
at the 2008 Midwinter Meeting of the Association for Research
in Otolaryngology (ARO).
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This is a short survey (5 mins) that aims to gather names of people who want to help the National Library for Health develop user centered services over the coming months.
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This is a short survey (5 mins) that aims to gather names of people who want to help the National Library for Health develop user centered services over the coming months.
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A cellular protein that helps guide immune cells to the gut has
been newly identified as a target of HIV when the virus begins
its assault on the body's immune system, according to researchers
from the National Institute of Allergy and Infectious Diseases
(NIAID), part of the National Institutes of Health (NIH).
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Patients with a certain gene variant drank less and experienced
better overall clinical outcomes than patients without the
variant while taking the medication naltrexone, according
to an analysis of participants in the National Institutes
of Health's 2001-2004 COMBINE (Combined Pharmacotherapies
and Behavioral Interventions for Alcohol Dependence) Study.
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A test developed by NIH scientists could greatly extend the survival
of infants with Menkes disease, a rare, otherwise fatal disorder
of copper metabolism. The scientists devised a test to diagnose
the condition early, when the chances for successful treatment
are greatest.
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The National Heart, Lung, and Blood Institute (NHLBI) of the National
Institutes of Health has stopped one treatment within a large,
ongoing North American clinical trial of diabetes and cardiovascular
disease 18 months early due to safety concerns after review of
available data, although the study will continue.
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There is no link between the MMR vaccination and autism, reported eight newspapers (5 February 2008). The newspaper reports were based on a well-conducted case-control study and were generally accurate. The study findings are likely to be reliable.
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There is no link between the MMR vaccination and autism, reported eight newspapers (5 February 2008). The newspaper reports were based on a well-conducted case-control study and were generally accurate. The study findings are likely to be reliable.
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There is no link between the MMR vaccination and autism, reported eight newspapers (5 February 2008). The newspaper reports were based on a well-conducted case-control study and were generally accurate. The study findings are likely to be reliable.
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3Rs was
unveiled today at a symposium marking the 10-year anniversary of
the Interagency Coordinating Committee on the Validation of Alternative
Methods (ICCVAM). ICCVAM is a permanent interagency committee
composed of representatives from 15 federal regulatory and research
agencies, including the National Institutes of Health (NIH),
that use, generate or disseminate toxicological information.
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The grossly disproportionate impact of HIV/AIDS on African Americans
is a public health crisis that we at the National Institutes of
Health (NIH) and as a nation must address boldly. Nearly 27 years
into the AIDS epidemic, approximately half of the new HIV infections
that occur each year in the United States are among African Americans,
even though they represent only 13 percent of the U.S. population.
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An improved understanding of how the immune system operates
during a viral infection is critical to designing successful anti-virus
vaccines. Scientists from the National Institute of Allergy and
Infectious Diseases (NIAID), part of the National Institutes of
Health (NIH), have added an important dimension to this knowledge.
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Certain variations in a gene that helps regulate response to stress
tend to protect adults who were abused in childhood from developing
depression, according to new research funded by the National Institute
of Mental Health (NIMH), part of the National Institutes of Health.
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An update of the evidence on this topic, produced by the NLH Respiratory Specialist Library
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An update of the evidence on this topic, produced by the NLH Respiratory Specialist Library
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Carl W. Dieffenbach, Ph.D., has been appointed Director of the
Division of AIDS (DAIDS) of the National Institute of Allergy and
Infectious Diseases (NIAID), a component of the National Institutes
of Health.
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Heart disease deaths in American women continued
to decline in 2005, and for the first time, have declined six years
consecutively, covering the years 2000-2005, according to newly
analyzed data announced today by the National Heart, Lung, and
Blood Institute (NHLBI) of the National Institutes of Health.
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The National Center for Complementary and Alternative Medicine
(NCCAM) welcomes six new members to the National Advisory Council
for Complementary and Alternative Medicine (NACCAM). The Council
serves as the principal advisory body to NCCAM, the lead Federal
agency for complementary and alternative medicine (CAM) research
and a component of the National Institutes of Health (NIH).
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Researchers analyzing prostate tumors have identified differences
in gene expression (the degree to which individual genes are turned
on or off) between African-American and European-American men that
show the existence of distinct tumor microenvironments (the area
that includes the tumor and the surrounding non-cancerous tissue)
in these two patient groups. These findings by researchers at the
National Cancer Institute (NCI), part of the National Institute
of Health, appeared online February 1, 2008, in "Cancer Research"
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Grant Information
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This Web site was made possible in part by NIH Grant Number R43 DK70418
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