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September 2007 - Posts
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Specific variations in two genes are linked to suicidal thinking
that sometimes occurs in people taking the most commonly prescribed
class of antidepressants, according to a large study led by scientists
at the National Institutes of Health's (NIH) National Institute
of Mental Health (NIMH). Depending on the particular mix inherited,
these versions increased the likelihood of such thoughts from 2-
to15-fold, the study found. About 1 percent of adult patients were
deemed to be at high genetic risk, 41 percent at elevated risk
and 58 percent at lower risk.
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An update of the evidence on this topic, produced by the NLH Women's Health and Screening Specialist Libraries
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An update of the evidence on this topic, produced by the NLH Complementary and Alternative Medicine (CAM) Specialist Library
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An update of the evidence on this topic, produced by the NLH Trauma and Orthopaedics Specialist Library, in conjunction with the Musculoskeletal Specialist Library
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A new contraceptive pill designed to be taken continuously, potentially eliminating menstrual periods, could soon be available in the UK, reported two newspapers (27 September 2007). The reports were partly based on a general article in New Scientist magazine which provided little information about the new pill.
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Researchers at the National Institutes of Health (NIH) have found
that more than 50 percent of the current asthma cases in the country
can be attributed to allergies, with approximately 30 percent of
those cases attributed to cat allergy.
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Giardia lamblia is a strange-looking parasite that swims in the
gut, spreads through stool, persists in contaminated water, and
is responsible for more than 20,000 reported infections a year
in the United States. Now it has finally spilled its genetic secrets.
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The Atlantic magazine,
will explore pressing bioscience issues and shed light on
cutting-edge scientific findings to improve the health of
the Nation.
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To accelerate the advancement of stem cell
biology from bench to bedside for treatment of cardiovascular
disease, the National Institutes of Health (NIH) will host
the scientific symposium Cardiovascular Regenerative Medicine
at the NIH Natcher Conference Center in Bethesda, Maryland.
Sessions will cover lessons learned from hematopoiesis, specification
and use of embryonic stem cells and adult stem cells, including
those derived from bone marrow (hematopoietic, endothelial
progenitor cells, and mesenchymal stem cells) and adult cardiac
stem cells that naturally reside in the heart; growth factors
to stimulate formation of new blood vessels (vascular regeneration)
and to repair or regenerate cardiac tissue (cardiac regeneration);
and technologies for monitoring cell activity.
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Women with advanced breast cancer survive longer after relapse if they continue to take Herceptin, reported three newspapers (26 September 2007). The reports were based on data presented at a conference and published in abstract form. The reports were broadly accurate but the quality of the research cannot be assessed.
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Journal of Neuroscience,
demonstrates for the first time a pathological pathway that ultimately
results in cell death related to frontotemporal dementia (FTD)
and amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's
disease). The discovery could eventually play a role in the design
of new drug therapies. The study was funded by the National Institute
on Aging (NIA) at the National Institutes of Health (NIH).
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New online resources stressing the importance of calcium for bone
health are now available for middle and high school teachers. The
resources are available through the Milk Matters calcium education
campaign, sponsored by the National Institute of Child Health and
Human Development of the National Institutes of Health.
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Acupuncture, including sham acupuncture, is more effective than conventional therapy for back pain, reported four newspapers (25th September 2007). The newspapers were generally accurate in their reports of a well conducted randomised controlled trial.
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Journal of
the American Medical Association. The study was funded by
the National Institutes of Health's National Institute of Mental
Health (NIMH).
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The National Institutes of Health (NIH) Office of Research on
Women’s Health (ORWH) and other co-sponsors announce the award
of more than $7 million to 15 new and continuing Building Interdisciplinary
Research Careers in Women’s Health (BIRCWH) programs nationwide.
This expands an innovative effort to foster career development
in women's health research with an emphasis on innovative interdisciplinary
mentoring across a variety of disciplines.
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The National Institutes of Health (NIH) Office of Research on Women's Health (ORWH) announces 11 new or continuing Specialized Center of Research (SCOR) on Sex and Gender Factors Affecting Women's Health Awards, as a result of the second solicitation for this program. Funding for these SCORs will total approximately $11 million per year for five years.
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Jeremy M. Berg, Ph.D., director of the National Institute of General Medical Sciences (NIGMS), has appointed Sally Lee as the institute’s new executive officer. NIGMS, a component of the National Institutes of Health (NIH), supports research that increases understanding of life processes and lays the foundation for advances in disease diagnosis, treatment, and prevention.
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More than 150 million people worldwide are infected with filarial parasites — long, thread-like worms that can live for years inside the human body and cause severe, debilitating diseases such as elephantiasis. Mosquitoes spread the larvae of these parasitic nematodes from human to human, placing at risk more than a billion people who live in places in Africa, Asia and Latin America where filarial parasites thrive.
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The National Kidney Disease Education Program (NKDEP), an initiative of the National Institutes of Health (NIH), has created an educational brochure tailored specifically for African Americans at risk for kidney disease. The brochure — "Kidney Disease: What African Americans Need to Know" — explains the connection between diabetes, high blood pressure, and kidney disease, and encourages those at risk to talk to their health care providers about getting tested.
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The rare immunodeficiency disorder known as Job’s syndrome is caused by a specific genetic mutation that both overstimulates and understimulates the human immune system, leading to harmful bacterial and fungal infections and the physical features characteristic of the syndrome, according to two independent groups of scientists, one from the National Institutes of Health (NIH) and the other from the Tokyo Medical and Dental University.
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An update of the evidence on this topic, produced by the NLH Emergency Care Specialist Library
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NIH Director Elias A. Zerhouni, M.D., is making a major investment in the future of science with five-year grants totaling more than $105 million to 41 exceptionally innovative investigators, many of whom are in the early stages of their careers.
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Two Institutes at the National Institutes of Health (NIH) have been honored with the prestigious Governors Award by the Academy of Television Arts and Sciences for their contribution to HBO’s Addiction Project. "Addiction" is a 14-part documentary television series and multimedia initiative revealing the science of addiction, its treatment, recovery, and its costs to families and society.
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National Institutes of Health (NIH) Director Elias A. Zerhouni, M.D., today announced the expansion of the national consortium that is transforming how clinical and translational research is conducted at academic health centers across the country. Ultimately, this consortium will enable researchers to provide new treatments more efficiently and quickly to patients. Funded through Clinical and Translational Science Awards (CTSAs), the consortium adds 12 more academic health centers to the 12 announced last October. When fully implemented in 2012, 60 institutions will be linked together to energize the discipline of clinical and translational science.
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Anthony S. Fauci, M.D., director of the National Institute of
Allergy and Infectious Diseases (NIAID) of the National Institutes
of Health (NIH), has been awarded the 2007 Mary Woodard Lasker
Award for Public Service for his role in developing two major U.S.
public health programs, in AIDS and biodefense. The award will
be presented on Friday, September 28th during a luncheon ceremony
in New York City.
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You can now search the Hitting the Headlines archive, and others
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A genetic variant present in nearly half of Americans of European
ancestry is linked to greater effectiveness of the smoking cessation
medication bupropion (Zyban), according to research by scientists
supported by the National Institute on Drug Abuse (NIDA) and the
National Cancer Institute (NCI), part of the National Institutes
of Health (NIH). People with this variant were less likely than
those without it to have resumed smoking six months after treatment
with bupropion.
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An update of the evidence on this topic, produced by the NLH Skin Disorders Specialist Library
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On 12 September 2007, seven newspapers (1-7) reported that the contraceptive pill protects women against cancer. These were generally accurate reports of a well conducted large retrospective study. The results are likely to be reliable for a population similar to that studied, but may not be generalisable to current oral contraceptive (OC) pill users.
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Control Your Diabetes. For Life.,
a national campaign that will reach out through a network of 200
partners to health care professionals and their patients to emphasize
the importance of comprehensive control of diabetes and CVD. The
NDEP is jointly sponsored by the National Institutes of Health
and the Centers for Disease Control and Prevention.
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The medication tamoxifen, best known as a treatment for breast
cancer, dramatically reduces symptoms of the manic phase of bipolar
disorder more quickly than many standard medications for the mental
illness, a new study shows. Researchers at the National Institutes
of Health's National Institute of Mental Health (NIMH) who conducted
the study also explained how: Tamoxifen blocks an enzyme called
protein kinase C (PKC) that regulates activities in brain cells.
The enzyme is thought to be over-active during the manic phase
of bipolar disorder.
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The National Institutes of Health (NIH) and NASA have entered into an agreement that helps American scientists utilize the International Space Station to answer questions about human health and diseases. The Memorandum of Understanding marks a milestone in a long partnership to advance scientific discovery and signals researchers to the availability of a remarkable platform on which to conduct experiments.
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Tendon, the cord-like tissue that connects muscle to bone, contains
a small subset of previously unknown adult stem cells, scientists
at the National Institute of Dental and Craniofacial Research (NIDCR)
part of the National Institutes of Health, and their colleagues
have discovered.
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The National Institutes of Health (NIH) and NASA will sign a Memorandum of Understanding (MOU) for cooperation in space-related health research. This agreement will help American scientists utilize the International Space Station to answer questions about human health and disease.
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The Lancet in
September 2007.
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The Lancet in
September 2007.
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Patients who switch from branded statins to a generic alternative, could have an increased risk of heat attack or stroke, reported three newspapers (6th September 2007). The reports are based on a conference abstract and press release. The reliability of the findings cannot be assessed as full study details are not available.
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The NIH’s Loan Repayment Program (LRP) Strength in Numbers campaign
debuted today. Offering a renewed commitment to qualified postdoctoral
scientists who are seeking careers in biomedical and behavioral
research, the program funds up to $35,000 annually in loan repayment.
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A genetic variation has been identified that increases the risk
of two chronic, autoimmune inflammatory diseases: rheumatoid arthritis
(RA) and systemic lupus erythematosus (lupus). These research findings
result from a long-time collaboration between the Intramural Research
Program (IRP) of the National Institute of Arthritis and Musculoskeletal
and Skin Diseases (NIAMS) and other organizations. NIAMS is part
of the National Institutes of Health.
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The National Institutes of Health (NIH) Roadmap for Medical Research will fund nine interdisciplinary research consortia as a means of integrating aspects of different disciplines to address health challenges that have been resistant to traditional research approaches.
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An update of the evidence on this topic, produced by the NLH Gastroenterology & Liver Diseases Specialist Library.
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Our ability to hear is made possible by way of a Rube Goldberg-style
process in which sound vibrations entering the ear shake and jostle
a successive chain of structures until, lo and behold, they are
converted into electrical signals that can be interpreted by the
brain. Exactly how the electrical signal is generated has been
the subject of ongoing research interest.
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A new clinical study will explore the brain-gut interaction in
patients with functional dyspepsia and whether certain drugs can
effectively relieve symptoms of this disorder. Functional dyspepsia
is a costly and chronic disorder that can cause severe stomach
pain often reported as cramping, bloating, and gas, or great discomfort
or fullness after eating. The study is funded by the National Institutes
of Health (NIH) at six medical centers in the U.S.
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Archives
of General Psychiatry
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The National Institutes of Health (NIH) has selected the first
projects to be funded as part of the Genes, Environment and Health
Initiative (GEI), a unique collaboration between geneticists and
environmental scientists.
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Clinical Cancer Research.
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A pill could reduce heart attacks and deaths if given to people with type 2 diabetes, reported three newspapers (3 September, 2007). The newspapers were generally accurate in their reports of a well-conducted trial. The extent to which the findings can be generalised to all individuals with type 2 diabetes is unclear.
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Grant Information
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This Web site was made possible in part by NIH Grant Number R43 DK70418
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